Clarithromycin is a semi-synthetic macrolide antibiotic. To reduce the development of drug-resistant bacteria and maintain the effectiveness of Clarithromycin and other antibacterial drugs are used. This drug should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
Mechanism of action :
• Clarithromycin is a bacteriostatic drug acts by inhibiting protein synthesis. • It binds reversibly to 50S ribosomal subunits of sensitive microorganism. • This drug interferes with transpeptidation and translocation thus • There is inhibition of protein synthesis and hence inhibition of cell growth.
Indications :
This drug is indicated for the treatment of adults with mild to moderate infection caused by susceptible strains of the designated microorganisms in the conditions listed below:
• Acute maxillary sinusitis due to Haemophilus influenzae Cheap Denver Broncos Hoodie , Moraxella catarrhalis, or Streptococcus pneumoniae • Acute bacterial exacerbation of chronic bronchitis due to Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis, or Streptococcus pneumoniae • Community-Acquired Pneumonia due to Haemophilus influenzae, Haemophilus parainfluenzae, Moraxella catarrhalis Customized Denver Broncos Jersey , Streptococcus pneumoniae, Chlamydia pneumoniae, or Mycoplasma pneumoniae
Side effects :
• uneven heartbeats, chest pain, shortness of breath; • diarrhea that is watery or bloody; • problems with your hearing; or • Severe skin reaction -- fever, sore throat, swelling in face or tongue Cheap Denver Broncos Jerseys , burning in eyes, skin pain, followed by a red or purple skin rash that spreads.
Contraindications :
• This product is contraindicated in patients with a known hypersensitivity to clarithromycin, erythromycin, or any of the macrolide antibiotics. • Concomitant administration of this medicine and any of the following drugs is contraindicated: cisapride, pimozide, astemizole Jamaal Charles Limited Jersey , terfenadine and ergotamine or dihydroergotamine .There have been postmarketing reports of drug interactions when clarithromycin andor erythromycin are coadministered with cisapride, pimozide, astemizole, or terfenadine resulting in cardiac arrhythmias (QT prolongation, ventricular tachycardia, ventricular fibrillation, and torsade de pointes) most likely due to inhibition of metabolism of these drugs by erythromycin and clarithromycin.
